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Cusco to Buenos Aires | Summer 2027

22 Days

  • Tour Description
  • Itinerary
  • Dates & prices
  • Enquire Now
  • Travel Insurance by Allianz

Tour Description

From high-altitude Cusco to the bold buzz of Buenos Aires, this stretch is pure Latin America energy. You'll trek the Inca Trail to Machu Picchu, cross Lake Titicaca, roll over the Uyuni Salt Flats, desert-hop through San Pedro, then swap it all for Argentina’s wine country and city charm. Mountains to metropolises. Trails and lakes. Deserts to tango streets. It’s 22 days of Peru, Bolivia and Argentina at their absolute best.

Priced From:

$ 5365pp *

From: 2027-01-17

To: 2028-01-02

Start Location: Cusco, Peru

End Location: Buenos Aires, Argentina

Trip Type: Latin America

Tour Advisors

Beccy Hayes

Travel Specialist

Tiffany McCrea-Lennon

Managing Director

Russell Mein

Travel Specialist

Caitlin Lennon

Travel Coordinator

Gaylyn Murdoch

Administration Manager

Holly Skene

Travel Co-ordinator

Kim Thomas

Broker

Itinerary

Cusco
Day 1
Duration: 1
Accommodation: Viajero Cusco (or similar)
Hello and welcome to Cusco! This afternoon is yours to settle in and start soaking up that high-altitude buzz. In the evening, you’ll meet your Trip Manager for a welcome meeting.
Cusco to Puno
Day 2
Duration: 1
Accommodation: Hotel Casona Plaza (or similar)
Today we’ll hop on board a shared coach once again and travel to Puno along the famous Route of the Sun, with iconic stops along the way — Andahuaylillas (AKA the “Sistine Chapel of the Americas”), Raqchi and the Temple of Wiracocha. Plus viewpoint and culture breaks at La Pascana, La Raya and the Pucará Museum. By the time we roll into Puno, we’ll have ticked off one of Peru’s best overland journeys. Welcome to the folkloric capital of Peru!
Puno to Lake Titicaca
Day 3
Duration: 1
Accommodation: Llachon Island Homestay (or similar)
Lake time! Today, we'll make our way to Lake Titicaca, cruising out across the lake towards Taquile Island. On the way, you’ll visit a floating island built from totora reeds, stepping onto the man-made platforms and checking out the reed houses up close. We'll explore a quieter part of Taquile on a short hike to an open-air market where the community shares dances, textiles, and local traditions. Then follow a pre-Incan path down to a sandy beach for some chill time. Hungry? Once we arrive on the Capachica Peninsula, we'll head into a local family homestay, and sit down for lunch made from local produce, with an optional late-afternoon hike up to a nearby hill for sunset. Later, after dinner, we’ll round things off with a small celebration of traditional music and dancing, then settle in for the night in basic but comfy rooms.
Lake Titicaca to Puno
Day 4
Duration: 1
Accommodation: Hotel Casona Plaza (or similar)
Say goodbye to your host fam. After an early brekkie, we'll boat back across the lake with the crew.  The rest of the day? All yours to do whatever you please.
Puno to La Paz
Day 5
Duration: 1
Accommodation: Hotel Las Brisas Centro (or similar)
Morning! Jump in to your private transfer from the hotel to the bus station, then roll out on the tourist bus to La Paz via Copacabana (about 10 hours). Settle in, snack up, and watch the landscapes do their thing. Welcome to Bolivia! Once we arrive, we'll snag a private transfer to the hotel. Come get your first taste of La Paz on a welcome dinner with your crew.
La Paz
Day 6
Duration: 1
Accommodation: Hotel Las Brisas Centro (or similar)
We'll kick off our La Paz discovery with a half-day Shoe Shiner City Tour and see the city through a local lens. You'll tick off viewpoints, street life, and big city energy. Then it’s free time to roam, market-hop, and snack your way through town. Ever heard of the Bolivian Fighting Cholitas? Tonight, you have the option to see them live in action.
La Paz to Sucre
Day 7
Duration: 1
Accommodation: Overnight Bus
Free day? To do La Paz your way? Mhm, that's right. Choose to cruise the city on Mi Teleférico for big Illimani views, wander the historic centre (San Francisco Church, Calle Jaén, Witches’ Market), or duck out to Valle de la Luna for those surreal, moon-like rock formations.  Later, we’ll take a private transfer to the bus station and hop on the overnight bus on a comfy ride to Sucre. Tonight we’ll be rolling through the dark towards Bolivia’s “White City,” ready to wake up in a whole new vibe.
Overnight Bus to Sucre
Day 8
Duration: 1
Accommodation: Hostal Sucre (or similar)
We'll arrive around 7am, then hop into a private transfer to the hotel to freshen up. Welcome to Bolivia’s “White City”! We'll explore the city on foot, checking out colonial streets, car-free plazas, and museums if you’re keen, and that chilled Spanish-era vibe. Thinking of what to grab for lunch? Check out Salteñería El Patio, Sucre's go-to spot for authentic Bolivian salteñas (juicy, baked empanadas stuffed with meat, cheese or veggies) in a charming colonial courtyard setting.
Sucre
Day 9
Duration: 1
Accommodation: Hostal Sucre (or similar)
It’s a free day to roam your way - whether that means browsing Mercado Central for fresh juices, street snacks and local handicrafts, or heading up Recoleta hill to catch sunset over the whitewashed rooftops and tiled domes. If you’re keen to get out of town, join us for an optional visit to the Maragua Crater to check out dinosaur footprints (no kidding!).
Sucre to Potosi
Day 10
Duration: 1
Accommodation: Hotel Virreyes (or similar)
This morning we’ll leave Sucre behind and roll by private transfer to Potosí, trading white-city charm for high-altitude history. This afternoon, we'll explore a city that wears its past loud and clear — cobbled streets, ornate colonial facades, and Cerro Rico looming over it all. We'll hit Plaza 10 de Noviembre for Cathedral views and local market energy, then dive into the Casa Nacional de la Moneda to see the silver-boom story up close (it’s equal parts fascinating and haunting).
Potosi
Day 11
Duration: 1
Accommodation: Hotel Virreyes (or similar)
You’ve got free time to explore your way, and if you’re curious, you can opt into a tour of the nearby mines for a deeper look at the city’s history. Tonight, we’ll share dinner with a local miner’s family and hear firsthand stories about life here.
Potosi to Uyuni
Day 12
Duration: 1
Accommodation: Samay Wasi (or similar)
We'll kick off today with a private transfer to Uyuni (around 4 hours), swapping colonial streets for wide-open Andean plains. First things first: a quick orientation of this dusty, high-altitude outpost, its adobe buildings and markets selling llama wool and quinoa. You’ll have the afternoon free to get prepped for the Salt Flats — snack run, anyone?
Uyuni to Uyuni Salt Flat
Day 13
Duration: 1
Accommodation: Hotel De Sal "Tambo Loma" - Colcha K (or similar)
After breakfast, you’ll jump into a private 4x4 with a Local Guide and head out into the wide-open weirdness. Kick things off at the Train Cemetery for rusted-locomotive photo ops and a hit of rail history, then roll through Colchani to see how salt is cut and processed and to browse the local handicraft stalls (yes, there are salt-brick shops). Quick stop at Plaza de las Banderas for a picnic-style lunch with flags snapping in the wind and nothing but white horizon for days. Then, we'll head to Incahuasi Island to walk among towering cacti. Later, we'll pull over on a perfectly flat stretch for those iconic perspective photos, before chasing sunset across the salar and finishing at a (very) remote salt hotel for dinner and a proper rest.
Uyuni Salt Flat to Reserva Nacional de Fauna Andina Eduardo Avaroa
Day 14
Duration: 1
Accommodation: Hotel Ecologico de Piedra (or similar)
Kick things off at the Ollagüe Volcano viewpoint, where a smoking peak cuts into endless salt plains and copper-toned hills. Then, we'll roll across the Altiplano to the lagoons of Cañapa, Chiarcota and Turquiri to see flamingos strut through neon-blue water (your camera will be working overtime here). Ready for surreal views? Here in Laguna Colorada, the lake glows red and white borax islands pop against a backdrop of distant volcanoes. From there, we'll climb higher into a geothermal field to check out hissing fumaroles and mud pots at nearly 5,000 metres. And if slowing it down sounds like your kind of plan, you're welcome to spend the rest of the day floating in the hot springs and taking in those unreal views.
Reserva Nacional de Fauna Andina Eduardo Avaroa to San Pedro de Atacama
Day 15
Duration: 1
Accommodation: Hostal Puritama (or similar)
After brekkie, we'll roll into landscapes that look straight out of a painting, starting with the Salvador Dalí Desert’s wind-sculpted rock formations. Then it’s on to Laguna Verde and Laguna Blanca for green and milky-white waters shimmering beneath towering volcanoes. After soaking up the final Bolivian views, we’ll cross the border into Chile, swap our 4x4s for a bus, and continue on towards San Pedro de Atacama. We'll arrive in San Pedro and check into our hostel before easing into this laid-back desert oasis. We'll spend tonight in this bohemian backpacker hub. Come sunset, the desert flips through shades of orange and pink, and by night the sky goes full stargazer mode.
San Pedro de Atacama
Day 16
Duration: 1
Accommodation: Hostal Puritama (or similar)
You’ll have a free day to take it at your own pace — sleep in, cafe crawl, or wander the dusty little streets. If you’re keen to level it up, you can opt into sandboarding for some desert thrills, or jump on the optional Vallecito sunset tour to chase golden-hour views.
San Pedro de Atacama to Salta
Day 17
Duration: 1
Accommodation: Hostal Prisamata (or similar)
Today, we'll jump on a public tourist bus for an epic Andean crossing to Salta (in around 10 hours). Expect big-window views as you climb out of the desert, pass salt flats and volcanoes, and hit the Chile–Argentina border at Paso de Jama (4,200m). After winding down into greener northwest Argentina and the Lerma Valley, you’ll arrive at Salta Bus Station and take a private transfer straight to your hostel.
Salta
Day 18
Duration: 1
Accommodation: Hostal Prisamata (or similar)
We'll kick with an orientation of the city centre, where leafy plazas, pastel colonial facades and arcaded cafes circle Plaza 9 de Julio, with the cathedral and San Francisco Church stealing the skyline. Then it’s a free day to do Salta your way — slow strolls, market wanderings, or cafe hopping. When night falls, you can opt into a Peña dinner & show, soaking up local folk music vibes alongside regional flavours in the streets that come alive after dark.
Salta to Buenos Aires
Day 19
Duration: 1
Accommodation: Viajero Hostel (or similar)
Say goodbye to Salta. Today, we're jumping on a plane straight to the capital of Argentina. Buenas! You've got the evening to spend exploring the streets of this city before we dive in deeper tomorrow.
Buenos Aires
Day 20
Duration: 1
Accommodation: Viajero Hostel (or similar)
Hola Argentina! We'll kick things off with an orientation to get you sorted, then the afternoon will be yours to explore. Hit the neighbourhoods, cafe-hop, people-watch, or just wander until something delicious finds you. For dinner tonight, opt in for an Argentine Sherpa dinner.
Buenos Aires
Day 21
Duration: 1
Accommodation: Viajero Hostel (or similar)
Today’s yours to dive deeper. You can opt for a trip out to Tigre and explore its riverside delta life. Back in Buenos Aires tonight, level things up with an optional dinner & tango Show — bold moves, big flavours, and pure Argentine drama (the good kind).
Buenos Aires
Day 22
Duration: 1
Buh-bye Buenos Aires - our time in South America has officially come to an end.

Dates & prices

Start Date: 2027-01-17
End Date: 2027-02-07
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Adult Price: 5365
Start Date: 2027-01-31
End Date: 2027-02-21
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